SCHEMBL29263189

SCHEMBL29263189

[Ti]C1CCc2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.52
PDPK1 O15530 1/20 0.52
CYP11B2 P19099 1/20 0.48
HTR6 P50406 1/20 0.47
RET P07949 1/20 0.45
HTR2A P28223 1/20 0.45
SLC22A1 O15245 1/20 0.44
PRCP P42785 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
SIGMAR1 Q99720 1/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11671198 0.77 SRD5A1 (0.55) IDO1PDPK1CYP11B2RETHTR2A
SCHEMBL10633202 0.75 IDO1 (0.52) IDO1PDPK1CYP11B2HTR6RET
Magnesium SCHEMBL31510119 0.75 SRD5A1 (0.53) IDO1PDPK1CYP11B2RETHTR2A
SCHEMBL9776721 0.73 IDO1 (0.50) IDO1PDPK1CYP11B2HTR6RET
SCHEMBL1973082 0.73 IDO1 (0.50) IDO1PDPK1CYP11B2HTR6RET
SCHEMBL23343810 0.73 IDO1 (0.50) IDO1PDPK1CYP11B2HTR6RET
SCHEMBL14647558 0.73 IDO1 (0.50) IDO1PDPK1CYP11B2RETHTR2A
SCHEMBL21114381 0.73 IDO1 (0.50) IDO1PDPK1CYP11B2RETHTR2A
SCHEMBL864856 0.73 IDO1 (0.50) IDO1PDPK1CYP11B2HTR6RET
SCHEMBL3418678 0.73 IDO1 (0.50) IDO1PDPK1CYP11B2RETHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184712-A Method for interfering with continuous movement of carbon atoms in organic molecules 河南省科学院化学研究所有限公司 2024-06-14 CN disclosed