SCHEMBL864856

SCHEMBL864856

[Na]C1CCc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.50
PDPK1 O15530 1/20 0.50
CYP11B2 P19099 1/20 0.47
ADRA1A P35348 1/20 0.44
RET P07949 1/20 0.43
HTR2A P28223 1/20 0.43
SIGMAR1 Q99720 2/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
HTR6 P50406 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10729425 0.86 IDO1 (0.53) IDO1PDPK1ADRA1A
SCHEMBL11671198 0.75 SRD5A1 (0.55) IDO1PDPK1CYP11B2RETHTR2A
SCHEMBL29263189 0.73 IDO1 (0.52) IDO1PDPK1CYP11B2RETHTR2A
Magnesium SCHEMBL31510119 0.73 SRD5A1 (0.53) IDO1PDPK1CYP11B2RETHTR2A
SCHEMBL8679389 0.73 IDO1 (0.52) IDO1PDPK1CYP11B2RETHTR2A
SCHEMBL10633202 0.73 IDO1 (0.52) IDO1PDPK1CYP11B2ADRA1ARET
SCHEMBL503849 0.73 SIGMAR1 (0.62) CYP11B2ADRA1AHTR2ASIGMAR1
SCHEMBL6667045 0.73 IDO1 (0.47) IDO1PDPK1CYP11B2RETHTR2A
SCHEMBL29390302 0.73 SIGMAR1 (0.62) CYP11B2ADRA1AHTR2ASIGMAR1
SCHEMBL23343810 0.71 IDO1 (0.50) IDO1PDPK1CYP11B2RETHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120093759-A1 Medical Devices, Wound Dressings, and Methods for Dressing Wounds VACHON DAVID J (US) 2012-04-19 US claimed
US-20260076977-A1 METHODS FOR TREATMENT OF DISEASES GALERA LABS LLC (US) 2026-03-19 US disclosed
WO-2025051102-A1 DEUTERATED TETRACYCLIC DERIVATIVE AND USE THEREOF 浙江我武翼方药业有限公司 2025-03-13 WO disclosed
CN-119591611-A Deuterated tetracyclic derivative and application thereof 浙江我武翼方药业有限公司 2025-03-11 CN disclosed
US-20250017944-A1 METHODS FOR TREATMENT OF DISEASES GALERA LABS, LLC 2025-01-16 US disclosed
US-12151028-B2 Drug delivery systems comprising solid solutions of weakly basic drugs ADARE PHARMACEUTICALS, INC. (US) 2024-11-26 US disclosed
US-20240335376-A1 GASTRORETENTIVE DOSAGE FORMS FOR SUSTAINED DRUG DELIVERY AMNEAL COMPLEX PRODUCTS RESEARCH LLC (US) 2024-10-10 US disclosed
US-12042559-B2 Gastroretentive dosage forms for sustained drug delivery AMNEAL COMPLEX PRODUCTS RES LLC (US) 2024-07-23 US disclosed
US-20240000701-A1 SELF-REGULATING OSMOTIC GASTRORETENTIVE DRUG DELIVERY SYSTEMS AMNEAL COMPLEX PRODUCTS RESEARCH LLC (US) 2024-01-04 US disclosed
US-20230404916-A1 GASTRORETENTIVE DOSAGE FORMS FOR SUSTAINED DRUG DELIVERY AMNEAL COMPLEX PRODUCTS RESEARCH LLC (US) 2023-12-21 US disclosed
WO-2002072034-A2 CHRONOTHERAPEUTIC DOSAGE FORMS PENWEST PHAMACEUTICALS CO. (US) 2002-09-19 WO disclosed
US-20020042394-A1 Cobalamin compounds useful as antibiotic agents and as imaging agents HOGENKAMP HENRICUS P C (US) 2002-04-11 US disclosed
WO-2002007707-A2 LINKAGE OF AGENTS USING MICROPARTICLES PERICOR SCIENCE, INC. (US) 2002-01-31 WO disclosed
WO-2001098317-A2 ALPHA-GLYCOSYLCERAMIDES FOR TREATING BACTERIAL AND FUNGAL INFECTIONS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2001-12-27 WO disclosed
WO-2001092288-A2 COBALAMIN COMPOUNDS USEFUL AS ANTIBIOTIC AGENTS AND AS IMAGING AGENTS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2001-12-06 WO disclosed
EP-1159293-A1 BACTERIAL TRANSGLYCOSYLASES: ASSAYS FOR MONITORING THE ACTIVITY USING LIPID II SUBSTRATE ANALOGS AND METHODS FOR DISCOVERING NEW ANTIBIOTICS PRINCETON UNIVERSITY (US) 2001-12-05 EP disclosed
WO-2000052035-A1 BACTERIAL TRANSGLYCOSYLASES: ASSAYS FOR MONITORING THE ACTIVITY USING LIPID II SUBSTRATE ANALOGS AND METHODS FOR DISCOVERING NEW ANTIBIOTICS PRINCETON UNIVERSITY (US) 2000-09-08 WO disclosed
US-5378474-A Pellet having a core including at least one highly soluble active ingredient and a coating partially soluble at high acidity; opiod drugs F. H. FAULDING & CO. LIMITED (AU) 1995-01-03 US disclosed
US-5330766-A Water soluble active ingredient core coated with matrix and enteric polymers; high speed, uniform release F. H. FAULDING & CO. LIMITED (AU) 1994-07-19 US disclosed
US-5202128-A Oral administering F. H. FAULDING & CO. LIMITED (AU) 1993-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250017944-A1 METHODS FOR TREATMENT OF DISEASES SOD1, GLS, GLS2 IDO1 3832/4885PDPK1 4040/4885CYP11B2 132/4885
US-20020042394-A1 Cobalamin compounds useful as antibiotic agents and as imaging agents MMAB, BLVRB, AHCY IDO1 61/4885PDPK1 3923/4885CYP11B2 3104/4885
US-20260076977-A1 METHODS FOR TREATMENT OF DISEASES SOD1, SOD3, CAT IDO1 3153/4885PDPK1 4735/4885CYP11B2 389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.