Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30462412 | 0.99 | SIGMAR1 (0.42) | SIGMAR1HSP90AA1HSP90AB1HSP90B1SUCNR1 | |
| SCHEMBL30462403 | 0.99 | SIGMAR1 (0.42) | SIGMAR1HSP90AA1HSP90AB1HSP90B1SUCNR1 | |
| SCHEMBL25234560 | 0.92 | HSP90AA1 (0.44) | SIGMAR1HSP90AA1HSP90AB1HSP90B1BCHE | |
| SCHEMBL25511637 | 0.86 | HSP90AA1 (0.45) | SIGMAR1HSP90AA1HSP90AB1HSP90B1MAOA | |
| SCHEMBL25511806 | 0.86 | HSP90AA1 (0.45) | SIGMAR1HSP90AA1HSP90AB1HSP90B1MAOA | |
| Hydrochloric Acid SCHEMBL30462425 | 0.85 | HSP90AA1 (0.44) | SIGMAR1HSP90AA1HSP90AB1HSP90B1MAOA | |
| Hydrochloric Acid SCHEMBL25229510 | 0.85 | HSP90AA1 (0.44) | SIGMAR1HSP90AA1HSP90AB1HSP90B1MAOA | |
| SCHEMBL30958009 | 0.84 | SUCNR1 (0.38) | SIGMAR1SUCNR1NAMPTDRD2BCHE | |
| SCHEMBL25208478 | 0.84 | HSP90AA1 (0.41) | SIGMAR1HSP90AA1HSP90AB1HSP90B1MAOA | |
| SCHEMBL25229325 | 0.84 | SIGMAR1 (0.37) | SIGMAR1SUCNR1DRD2BCHECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317954-A | Indoline as PROTAC compound | 奈奥芬莱有限公司 | 2024-07-09 | — | — | CN | disclosed |