Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.69 |
| ▸ | MEN1 | O00255 | 11/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HTR1E | P28566 | 1/20 | 0.58 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.58 |
| ▸ | PHGDH | O43175 | 2/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16063996 | 0.85 | MAPT (0.76) | MAPTKMT2AMEN1MAPK1POLB | |
| SCHEMBL13497044 | 0.83 | MAPT (0.73) | MAPTKMT2AMEN1MAPK1POLB | |
| SCHEMBL13497045 | 0.80 | MAPT (0.71) | MAPTKMT2AMEN1MAPK1POLB | |
| SCHEMBL13497040 | 0.79 | MAPT (0.83) | MAPTKMT2AMEN1MAPK1POLB | |
| SCHEMBL29264529 | 0.79 | MAPT (1.00) | MAPTKMT2AMEN1MAPK1POLB | |
| SCHEMBL30307761 | 0.79 | MAPT (1.00) | MAPTKMT2AMEN1MAPK1POLB | |
| SCHEMBL29264533 | 0.78 | MAPT (0.68) | MAPTKMT2AMEN1MAPK1POLB | |
| SCHEMBL12417172 | 0.78 | MAPT (1.00) | MAPTKMT2AMEN1MAPK1POLB | |
| SCHEMBL13497043 | 0.77 | MAPT (0.67) | MAPTKMT2AMEN1MAPK1POLB | |
| SCHEMBL30307769 | 0.77 | MAPT (0.66) | MAPTKMT2AMEN1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819414-A | N-acyl-containing aryl hydrazone derivatives, and preparation method and application thereof | 沈阳药科大学 | 2023-03-21 | — | — | CN | claimed |
| CN-115819414-B | N-acyl-containing aryl hydrazone derivative and preparation method and application thereof | 沈阳药科大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-115819414-A | N-acyl-containing aryl hydrazone derivatives, and preparation method and application thereof | 沈阳药科大学 | 2023-03-21 | — | — | CN | disclosed |