Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 17/20 | 1.00 |
| ▸ | POLB | P06746 | 5/20 | 1.00 |
| ▸ | PSMD14 | O00487 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | APAF1 | O14727 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | LDHA | P00338 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264529 | 1.00 | MAPT (1.00) | MAPTPOLBPSMD14ALDH1A1APAF1 | |
| SCHEMBL29264536 | 0.84 | MAPT (0.73) | MAPTPOLBPSMD14ALDH1A1L3MBTL1 | |
| SCHEMBL13497045 | 0.83 | MAPT (0.71) | MAPTPOLBPSMD14ALDH1A1L3MBTL1 | |
| SCHEMBL16063996 | 0.81 | MAPT (0.76) | MAPTPOLBPSMD14ALDH1A1L3MBTL1 | |
| SCHEMBL6721166 | 0.80 | MAPT (1.00) | MAPTPOLBPSMD14ALDH1A1APAF1 | |
| SCHEMBL13497044 | 0.80 | MAPT (0.73) | MAPTPOLBPSMD14ALDH1A1L3MBTL1 | |
| SCHEMBL29264530 | 0.79 | MAPT (0.69) | MAPTPOLBPSMD14ALDH1A1L3MBTL1 | |
| SCHEMBL30307755 | 0.79 | MAPT (0.79) | MAPTPOLBPSMD14ALDH1A1L3MBTL1 | |
| SCHEMBL13496985 | 0.79 | MAPT (0.80) | MAPTPOLBPSMD14ALDH1A1APAF1 | |
| SCHEMBL18153643 | 0.79 | MAPT (0.80) | MAPTPOLBPSMD14ALDH1A1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819414-A | N-acyl-containing aryl hydrazone derivatives, and preparation method and application thereof | 沈阳药科大学 | 2023-03-21 | — | — | CN | claimed |
| CN-115819414-B | N-acyl-containing aryl hydrazone derivative and preparation method and application thereof | 沈阳药科大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-115819414-A | N-acyl-containing aryl hydrazone derivatives, and preparation method and application thereof | 沈阳药科大学 | 2023-03-21 | — | — | CN | disclosed |