Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 2/20 | 0.48 |
| ▸ | CCNK | O75909 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264678 | 0.85 | CCR6 (0.76) | CCR6CDK2CCNKCCNA2CDK12 | |
| SCHEMBL29264663 | 0.80 | GAA (0.58) | CCR6GAACDK2CCNKCCNA2 | |
| SCHEMBL30284876 | 0.77 | GAA (0.60) | CCR6GAACDK2CCNKCCNA2 | |
| SCHEMBL25079568 | 0.77 | GAA (0.60) | CCR6GAACDK2CCNKCCNA2 | |
| SCHEMBL24529809 | 0.73 | GAA (0.53) | CCR6GAACDK2CCNKCCNA2 | |
| SCHEMBL29264660 | 0.73 | GAA (0.52) | CCR6GAACDK2CCNKCCNA2 | |
| SCHEMBL25079508 | 0.73 | CCR6 (0.54) | CCR6GAACDK2CCNKCCNA2 | |
| SCHEMBL25079907 | 0.72 | CCR6 (0.52) | CCR6GAACDK2CCNKCCNA2 | |
| SCHEMBL29264668 | 0.72 | CCR6 (0.73) | CCR6GAACDK2CCNKCCNA2 | |
| SCHEMBL31155708 | 0.72 | EPHX2 (0.65) | CCR6GAACDK2EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019735-A | Arylsulfonyl compounds as CCR6 inhibitors | 坎莫森特里克斯公司 | 2024-05-10 | — | — | CN | disclosed |