Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CCR6 | P51684 | 5/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.53 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CCNK | O75909 | 1/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31155671 | 0.85 | EPHX2 (0.59) | CCR6EPHX1EPHX2MEN1KMT2A | |
| SCHEMBL31155666 | 0.85 | CCR6 (0.48) | GAACCR6EPHX1EPHX2MEN1 | |
| SCHEMBL31155681 | 0.83 | CCR6 (0.70) | CCR6EPHX2MEN1KMT2ALMNA | |
| SCHEMBL25079833 | 0.83 | CCR6 (0.77) | GAACCR6CCNKCCNA2CDK2 | |
| SCHEMBL32670559 | 0.83 | CCR6 (0.49) | GAACCR6EPHX1EPHX2MEN1 | |
| SCHEMBL32670381 | 0.82 | USP5 (0.55) | CCR6EPHX2LMNAALDH1A1 | |
| SCHEMBL26095584 | 0.82 | TRPV4 (0.50) | GAAEPHX1EPHX2TRPV4MEN1 | |
| SCHEMBL23577993 | 0.81 | USP5 (0.58) | GAAEPHX2TRPV4MEN1KMT2A | |
| SCHEMBL24529809 | 0.80 | GAA (0.53) | GAACCR6EPHX1EPHX2TRPV4 | |
| SCHEMBL29264665 | 0.80 | CCR6 (0.54) | GAACCR6EPHX1EPHX2TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019735-A | Arylsulfonyl compounds as CCR6 inhibitors | 坎莫森特里克斯公司 | 2024-05-10 | — | — | CN | disclosed |