SCHEMBL29264682

SCHEMBL29264682

CC(C)(C)OC(=O)NCc1ccc(COC(=O)n2ccnc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 4/20 0.47
L3MBTL1 Q9Y468 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
NTSR1 P30989 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 6/20 0.42
TDP1 Q9NUW8 5/20 0.42
MAPK1 P28482 1/20 0.42
KDM4E B2RXH2 2/20 0.41
NPSR1 Q6W5P4 3/20 0.40
HDAC1 Q13547 1/20 0.40
RECQL P46063 1/20 0.40
GPR55 Q9Y2T6 2/20 0.40
BRD4 O60885 1/20 0.40
POLB P06746 1/20 0.40
XBP1 P17861 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4615564 0.86 NAMPT (0.51) NAMPTL3MBTL1GAAMAPTTDP1
SCHEMBL16273477 0.81 CYP3A4 (0.44) L3MBTL1GAAMAPTTDP1KDM4E
SCHEMBL28537669 0.78 SIRT2 (0.47) NAMPTMEN1KMT2AMAPTBRD4
SCHEMBL16272989 0.76 CYP17A1 (0.36) L3MBTL1MEN1KMT2ATDP1BRD4
SCHEMBL1621471 0.76 CYP19A1 (0.42) NAMPTMEN1KMT2AMAPTKDM4E
SCHEMBL12016602 0.76 HTT (0.53) NAMPTGAAMAPTMAPK1KDM4E
SCHEMBL3180689 0.75 L3MBTL1 (0.61) NAMPTL3MBTL1GAAMAPTTDP1
SCHEMBL12016595 0.75 CYP19A1 (0.52)
SCHEMBL16273429 0.75 CA12 (0.51) MEN1KMT2AGAATDP1NPSR1
SCHEMBL432657 0.75 KMT2A (0.49) L3MBTL1MEN1KMT2ATDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240398963-A1 DRUG DELIVERY SYSTEM FOR LOCALLY DELIVERING THERAPEUTIC AGENTS AND USES THEREOF COVAL BIOPHARMA (SHANGHAI) CO., LTD. (CN) 2024-12-05 US disclosed
CN-118019750-A Drug delivery system for local delivery of therapeutic agents and uses thereof 上海椿安生物医药科技有限公司 2024-05-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240398963-A1 DRUG DELIVERY SYSTEM FOR LOCALLY DELIVERING THERAPEUTIC AGENTS AND USES THEREOF TIE1, KDR, TEK NAMPT 1597/4885L3MBTL1 1821/4885MEN1 2974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.