Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.64 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.64 |
| ▸ | PI4KB | Q9UBF8 | 15/20 | 0.61 |
| ▸ | PIK3C2G | O75747 | 2/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29265060 | 0.91 | PIK3CD (0.63) | PIK3CDPIK3CGPI4KBPIK3C2GPIK3CA | |
| SCHEMBL29265053 | 0.88 | PI4KB (0.62) | PIK3CDPIK3CGPI4KBPIK3C2GPIK3CA | |
| SCHEMBL29265065 | 0.84 | PIK3CD (0.81) | PIK3CDPIK3CGPI4KBPIK3C2GPIK3CA | |
| SCHEMBL30792284 | 0.81 | PIK3CD (0.58) | PIK3CDPIK3CGPI4KBPIK3C2GPIK3CA | |
| SCHEMBL29265059 | 0.80 | HDAC1 (0.46) | PIK3CDPIK3CGPI4KB | |
| SCHEMBL29265081 | 0.80 | PIK3CD (0.66) | PIK3CDPIK3CGPI4KBPIK3C2GPIK3CA | |
| SCHEMBL1545939 | 0.79 | PIK3CD (0.81) | PIK3CDPIK3CGPI4KBPIK3C2GPIK3CA | |
| SCHEMBL14851581 | 0.79 | PIK3C2G (0.79) | PIK3CDPIK3CGPI4KBPIK3C2GPIK3CA | |
| SCHEMBL48677 | 0.78 | PIK3CD (1.00) | PIK3CDPIK3CGPI4KBPIK3C2GPIK3CA | |
| SCHEMBL48522 | 0.78 | PIK3CD (0.82) | PIK3CDPIK3CGPI4KBPIK3C2GPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221610-A | Phenylthiazole amine PI4KIII beta/HDAC double-target inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-118221610-A | Phenylthiazole amine PI4KIII beta/HDAC double-target inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-06-21 | — | — | CN | disclosed |