Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29265062 | 0.89 | MAPT (0.52) | HDAC1HDAC2PI4KB | |
| SCHEMBL29265051 | 0.87 | MAPT (0.51) | HDAC1HDAC2PI4KB | |
| SCHEMBL29265058 | 0.80 | PIK3CD (0.64) | PIK3CDPIK3CGPI4KB | |
| SCHEMBL29265077 | 0.80 | MAPT (0.51) | PI4KB | |
| SCHEMBL29265053 | 0.75 | PI4KB (0.62) | PIK3CDPIK3CGPI4KB | |
| SCHEMBL29265068 | 0.75 | MEN1 (0.52) | HDAC1HDAC6HDAC2HDAC3HDAC8 | |
| SCHEMBL29265060 | 0.71 | PIK3CD (0.63) | PIK3CDPIK3CGPI4KB | |
| SCHEMBL30792284 | 0.71 | PIK3CD (0.58) | PIK3CDPIK3CGPI4KB | |
| SCHEMBL29265072 | 0.69 | MAPT (0.53) | PI4KB | |
| Butyric Acid SCHEMBL29265074 | 0.69 | MAPT (0.53) | PI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221610-A | Phenylthiazole amine PI4KIII beta/HDAC double-target inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-118221610-A | Phenylthiazole amine PI4KIII beta/HDAC double-target inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-06-21 | — | — | CN | disclosed |