Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.30 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29265377 | 0.83 | ESR1 (0.34) | LMNAESR1ALDH1A1L3MBTL1 | |
| SCHEMBL29265375 | 0.75 | ALDH1A1 (0.52) | GLALMNAALDH1A1L3MBTL1 | |
| SCHEMBL27719166 | 0.74 | ALDH1A1 (0.40) | LMNAALDH1A1L3MBTL1 | |
| SCHEMBL29265376 | 0.73 | TDP1 (0.43) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL28655118 | 0.70 | ALDH1A1 (0.44) | GLALMNAALDH1A1L3MBTL1 | |
| SCHEMBL16245561 | 0.69 | ALDH1A1 (0.54) | GLALMNAALDH1A1L3MBTL1 | |
| SCHEMBL11481725 | 0.69 | GLA (0.33) | GLALMNA | |
| SCHEMBL29265244 | 0.68 | ALDH1A1 (0.35) | GLALMNAALDH1A1 | |
| SCHEMBL11481731 | 0.68 | GLA (0.32) | GLALMNAALDH1A1L3MBTL1 | |
| SCHEMBL28231830 | 0.68 | CA12 (0.48) | GLALMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118176194-A | Conjugates comprising covalent binding agents for targeting intracellular proteins | 瑞择生物公司 | 2024-06-11 | — | — | CN | disclosed |