Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.61 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.52 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.52 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL29267977 | 1.00 | GSR (0.61) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Lysine SCHEMBL28699455 | 1.00 | GSR (0.61) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Lysine SCHEMBL28695050 | 1.00 | GSR (0.61) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Lysine SCHEMBL28695052 | 1.00 | GSR (0.61) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Lysine SCHEMBL28699457 | 1.00 | GSR (0.61) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Tetrahexylammonium SCHEMBL28700732 | 0.91 | GSR (0.65) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Tetrahexylammonium SCHEMBL28700729 | 0.91 | GSR (0.65) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Lysine SCHEMBL9404153 | 0.89 | GSR (0.77) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Dodecylamine SCHEMBL9441764 | 0.89 | GSR (0.77) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Octadecylamine SCHEMBL9458206 | 0.89 | GSR (0.77) | GSRGNAI3GNAO1GNAI1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118065002-A | Radiation-resistant polymer network flexible wearable material and preparation method thereof | 四川大学 | 2024-05-24 | — | — | CN | disclosed |