Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | GNRHR | P30968 | 1/20 | 0.49 |
| ▸ | IL1B | P01584 | 2/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29268419 | 0.84 | NPC1 (0.61) | TP53LMNAKMT2AMEN1MAPT | |
| SCHEMBL13947430 | 0.82 | KDM4E (0.80) | KDM4EPKMTP53LMNAKMT2A | |
| SCHEMBL30100433 | 0.81 | KDM4E (0.62) | KDM4EPKMTP53LMNAKMT2A | |
| SCHEMBL23675376 | 0.81 | KDM4E (0.62) | KDM4EPKMTP53LMNAKMT2A | |
| SCHEMBL20615733 | 0.79 | KDM4E (0.79) | KDM4EPKMTP53LMNAKMT2A | |
| SCHEMBL3341330 | 0.79 | KDM4E (0.53) | KDM4EPKMTP53LMNAKMT2A | |
| SCHEMBL24766315 | 0.78 | KDM4E (0.61) | KDM4EPKMTP53LMNAKMT2A | |
| SCHEMBL2601854 | 0.78 | HTR4 (0.66) | — | |
| SCHEMBL24896483 | 0.78 | KDM4E (0.48) | KDM4EPKMTP53LMNAKMT2A | |
| SCHEMBL1313080 | 0.78 | KDM4E (0.66) | KDM4EPKMTP53LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324682-A | 2-Oxo-acetamide compound, pharmaceutical composition containing same and application thereof | 中国药科大学 | 2024-07-12 | — | — | CN | disclosed |