SCHEMBL29268802

SCHEMBL29268802

c1ccc(-c2coc3ccc4ccccc4c23)c(-c2ccc3cc4ccccc4cc3c2-c2ccccc2-c2coc3ccc4ccccc4c23)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.42
POLB P06746 2/20 0.41
PTPN1 P18031 1/20 0.41
KDM4E B2RXH2 3/20 0.40
DNMT1 P26358 1/20 0.39
MAPT P10636 6/20 0.38
MEN1 O00255 5/20 0.38
KMT2A Q03164 5/20 0.38
ALDH1A1 P00352 5/20 0.38
LMNA P02545 2/20 0.38
AHR P35869 2/20 0.36
CES1 P23141 1/20 0.36
HIF1A Q16665 2/20 0.36
HSD17B10 Q99714 2/20 0.36
CYP1B1 Q16678 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29268799 0.92 ANPEP (0.42) ANPEPPOLBPTPN1KDM4EDNMT1
SCHEMBL30009774 0.81 POLB (0.56) POLBPTPN1KDM4EMAPTMEN1
SCHEMBL9131092 0.79 DNMT1 (0.47) ANPEPKDM4EDNMT1MAPTMEN1
SCHEMBL21617935 0.78 DNMT1 (0.49) ANPEPKDM4EDNMT1MAPTMEN1
SCHEMBL30332774 0.77 ALDH1A1 (0.39) ANPEPPOLBPTPN1DNMT1MAPT
SCHEMBL30302851 0.75 ANPEP (0.38) ANPEPPOLBPTPN1DNMT1MAPT
SCHEMBL30302829 0.75 ALDH1A1 (0.41) ANPEPPOLBPTPN1DNMT1MEN1
SCHEMBL27356640 0.74 POLB (0.47) POLBPTPN1KDM4EMAPTMEN1
SCHEMBL11866119 0.74 MAPT (0.54) POLBPTPN1KDM4EMAPTMEN1
SCHEMBL11830152 0.74 KDM4E (0.49) POLBPTPN1KDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118339941-A Mixed powder and method for producing same, method for producing organic electroluminescent element using same, method for selecting compound in mixed powder, and composition for vacuum vapor deposition 出光兴产株式会社 2024-07-12 CN disclosed