Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25248700 | 1.00 | FAAH (0.46) | FAAHUSP30CES1SCDGRM5 | |
| SCHEMBL29268923 | 1.00 | FAAH (0.46) | FAAHUSP30CES1SCDGRM5 | |
| SCHEMBL25213510 | 0.90 | FAAH (0.46) | FAAHUSP30CES1SCDGRM5 | |
| SCHEMBL25215762 | 0.90 | FAAH (0.42) | FAAHUSP30CES1SCDGRM5 | |
| SCHEMBL30474001 | 0.90 | FAAH (0.39) | FAAHUSP30GRM5HDAC1HDAC6 | |
| SCHEMBL25675481 | 0.90 | FAAH (0.39) | FAAHUSP30GRM5HDAC1HDAC6 | |
| SCHEMBL25218096 | 0.89 | HDAC1 (0.46) | FAAHUSP30HDAC1HDAC6CA12 | |
| SCHEMBL25210893 | 0.89 | HDAC1 (0.46) | FAAHUSP30HDAC1HDAC6HDAC3 | |
| SCHEMBL25215194 | 0.88 | FAAH (0.49) | FAAHUSP30CES1SCDGRM5 | |
| SCHEMBL25218982 | 0.88 | FAAH (0.49) | FAAHUSP30CES1SCDGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302422-A | Substituted N-cyanopyrrolidines having activity as USP30 inhibitors | 特殊治疗有限公司 | 2024-07-05 | — | — | CN | disclosed |