Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30473927 | 1.00 | FAAH (0.41) | FAAHEGLN2F2RUSP30HDAC1 | |
| SCHEMBL25676348 | 1.00 | FAAH (0.41) | FAAHEGLN2F2RUSP30HDAC1 | |
| SCHEMBL29268979 | 1.00 | FAAH (0.41) | FAAHEGLN2F2RUSP30HDAC1 | |
| SCHEMBL30473956 | 0.91 | FAAH (0.41) | FAAHEGLN2F2RUSP30HDAC1 | |
| SCHEMBL29268911 | 0.91 | FAAH (0.41) | FAAHEGLN2F2RUSP30HDAC1 | |
| SCHEMBL29268912 | 0.91 | FAAH (0.41) | FAAHEGLN2F2RUSP30HDAC1 | |
| SCHEMBL30474010 | 0.90 | FAAH (0.39) | FAAHEGLN2F2RUSP30HDAC1 | |
| SCHEMBL25675481 | 0.90 | FAAH (0.39) | FAAHEGLN2F2RUSP30HDAC1 | |
| SCHEMBL30474001 | 0.90 | FAAH (0.39) | FAAHEGLN2F2RUSP30HDAC1 | |
| SCHEMBL29268964 | 0.89 | FAAH (0.39) | FAAHEGLN2F2RUSP30HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302422-A | Substituted N-cyanopyrrolidines having activity as USP30 inhibitors | 特殊治疗有限公司 | 2024-07-05 | — | — | CN | disclosed |