Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | KAT7 | O95251 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29269492 | 1.00 | YAP1 (0.42) | YAP1P2RX7BCHEACHECACNA1F | |
| SCHEMBL30283502 | 1.00 | YAP1 (0.42) | YAP1P2RX7BCHEACHECACNA1F | |
| SCHEMBL29269318 | 0.93 | BCHE (0.43) | YAP1P2RX7BCHEACHECACNA1F | |
| SCHEMBL30283202 | 0.93 | BCHE (0.43) | YAP1P2RX7BCHEACHECACNA1F | |
| SCHEMBL29269320 | 0.93 | BCHE (0.43) | YAP1P2RX7BCHEACHECACNA1F | |
| SCHEMBL29269481 | 0.92 | YAP1 (0.42) | YAP1P2RX7BCHEACHECACNA1F | |
| SCHEMBL29269479 | 0.92 | YAP1 (0.42) | YAP1P2RX7BCHEACHECACNA1F | |
| SCHEMBL30283447 | 0.92 | YAP1 (0.42) | YAP1P2RX7BCHEACHECACNA1F | |
| SCHEMBL29269486 | 0.90 | BCHE (0.44) | YAP1P2RX7BCHEACHECACNA1F | |
| SCHEMBL30283245 | 0.90 | BCHE (0.44) | YAP1P2RX7BCHEACHECACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118251383-A | Macrocyclic compounds as proteasome beta subunit type 5 inhibitors | 利德探索中心有限公司 | 2024-06-25 | — | — | CN | disclosed |