SCHEMBL29270366

SCHEMBL29270366

Nc1cnccc1C(=O)O.Nc1cnccc1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 14/20 1.00
KDM6B O15054 7/20 1.00
KDM4D Q6B0I6 4/20 1.00
KDM4E B2RXH2 3/20 1.00
ALDH1A1 P00352 2/20 1.00
KDM4A O75164 2/20 1.00
MEN1 O00255 1/20 1.00
MAPT P10636 1/20 1.00
THRB P10828 1/20 1.00
KMT2A Q03164 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
GLA P06280 1/20 0.61
GAA P10253 1/20 0.61
NAPRT Q6XQN6 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29643531 1.00 KDM4C (1.00) KDM4CKDM6BKDM4DKDM4EALDH1A1
SCHEMBL535569 1.00 KDM4C (1.00) KDM4CKDM6BKDM4DKDM4EALDH1A1
Bromide SCHEMBL5768959 0.98 KDM4C (0.96) KDM4CKDM6BKDM4DKDM4EALDH1A1
Nitrous Acid SCHEMBL29105410 0.92 KDM4C (0.85) KDM4CKDM6BKDM4DKDM4EALDH1A1
Pyridine SCHEMBL29170612 0.91 KDM4C (0.82) KDM4CKDM6BKDM4DKDM4EALDH1A1
SCHEMBL1643711 0.84 KDM4C (0.73) KDM4CKDM6BKDM4DKDM4EALDH1A1
SCHEMBL244632 0.83 KDM4C (0.70) KDM4CKDM6BKDM4DKDM4EALDH1A1
SCHEMBL220890 0.83 KDM4C (0.70) KDM4CKDM6BKDM4DKDM4EALDH1A1
SCHEMBL2139056 0.83 KDM4E (0.70) KDM4CKDM6BKDM4DKDM4EALDH1A1
SCHEMBL30785801 0.83 KDM4C (0.70) KDM4CKDM6BKDM4DKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325106-A Cd-MOF material based on aminoisonicotinic acid, preparation method and application 中原工学院 2024-07-12 CN disclosed