SCHEMBL535569

SCHEMBL535569

Nc1cnccc1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 14/20 1.00
KDM6B O15054 7/20 1.00
KDM4D Q6B0I6 4/20 1.00
KDM4E B2RXH2 3/20 1.00
ALDH1A1 P00352 2/20 1.00
KDM4A O75164 2/20 1.00
MEN1 O00255 1/20 1.00
MAPT P10636 1/20 1.00
THRB P10828 1/20 1.00
KMT2A Q03164 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
GLA P06280 1/20 0.61
GAA P10253 1/20 0.61
NAPRT Q6XQN6 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29270366 1.00 KDM4C (1.00) KDM4CKDM6BKDM4DKDM4EALDH1A1
SCHEMBL29643531 1.00 KDM4C (1.00) KDM4CKDM6BKDM4DKDM4EALDH1A1
Bromide SCHEMBL5768959 0.98 KDM4C (0.96) KDM4CKDM6BKDM4DKDM4EALDH1A1
Nitrous Acid SCHEMBL29105410 0.92 KDM4C (0.85) KDM4CKDM6BKDM4DKDM4EALDH1A1
Pyridine SCHEMBL29170612 0.91 KDM4C (0.82) KDM4CKDM6BKDM4DKDM4EALDH1A1
SCHEMBL1643711 0.84 KDM4C (0.73) KDM4CKDM6BKDM4DKDM4EALDH1A1
SCHEMBL244632 0.83 KDM4C (0.70) KDM4CKDM6BKDM4DKDM4EALDH1A1
SCHEMBL220890 0.83 KDM4C (0.70) KDM4CKDM6BKDM4DKDM4EALDH1A1
SCHEMBL2139056 0.83 KDM4E (0.70) KDM4CKDM6BKDM4DKDM4EALDH1A1
SCHEMBL30785801 0.83 KDM4C (0.70) KDM4CKDM6BKDM4DKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 958 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037213-A MOFs material with ultrahigh ammonia adsorption, preparation method and application thereof 洛阳师范学院 2026-05-15 CN claimed
CN-119869482-A Preparation method and application of deep coal gas methane adsorbent based on graphene and MOF composite material 陕西科技大学 2025-04-25 CN claimed
CN-118580512-A Multi-cage iron-based organic framework material and preparation method and application thereof 陕西师范大学 2024-09-03 CN claimed
CN-118515883-A Metal-organic framework material for separating ethane/ethylene mixed gas and preparation method and application thereof 西安交通大学 2024-08-20 CN claimed
CN-118477629-A MOFs material for decarbonizing coalbed methane and preparation method and application thereof 振西远景(陕西)科技合伙企业(有限合伙) 2024-08-13 CN claimed
CN-118459828-A Composite polysaccharide microsphere and preparation method and application thereof 中科森辉微球技术(苏州)有限公司 2024-08-09 CN claimed
CN-118325106-A Cd-MOF material based on aminoisonicotinic acid, preparation method and application 中原工学院 2024-07-12 CN claimed
US-11992563-B2 Composite material for rapid blood clotting and preparation method thereof GUANGDONG OCEAN UNIVERSITY (CN) 2024-05-28 US claimed
CN-113387881-B Synthesis method of 3-aminoisonicotinic acid methyl ester 安徽大学 2024-05-14 CN claimed
CN-117986604-A Copper-based metal framework and preparation method thereof 天津理工大学 2024-05-07 CN claimed
US-9783905-B2 Reaction products of amino acids and epoxies Rohm and Haas Electronic Mateirals LLC (US) 2017-10-10 US claimed
US-20170218533-A1 REACTION PRODUCTS OF AMINO ACIDS AND EPOXIES U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2017-08-03 US claimed
CN-106831768-A A kind of synthetic method of 2,6 dichloropyridines [3,4 B] pyrazine 瑞孚信江苏药业股份有限公司 2017-06-13 CN claimed
CN-104130256-B A kind of pyrido [3,4-d] pyrimidine-4(3H) preparation method of-one derivative 上海毕得医药科技有限公司 2016-08-24 CN claimed
CN-105233873-A Preparation method of large-particle carrier loading hydrosilylation catalyst HARBIN INST OF TECHNOLOGY 2016-01-13 CN claimed
CN-104130256-A Preparation method for pyridine[3, 4-d]pyrimidine-4(3H)-one derivative BIDE PHARMATECH LTD 2014-11-05 CN claimed
WO-2012052179-A1 AMINO DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE SKIN DISORDERS ALMIRALL, S.A. (ES) 2012-04-26 WO claimed
WO-2012052180-A1 COMBINATIONS COMPRISING DHODH INHIBITORS AND COX INHIBITORS ALMIRALL, S.A. (ES) 2012-04-26 WO claimed
EP-2444088-A1 Amino derivatives for the treatment of proliferative skin disorders Almirall, S.A. (ES) 2012-04-25 EP claimed
EP-2444086-A1 Combinations comprising DHODH inhibitors and COX inhibitors Almirall, S.A. (ES) 2012-04-25 EP claimed