Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29270741 | 0.90 | USP30 (0.34) | USP30PDK2BACE1BACE2 | |
| SCHEMBL26961463 | 0.87 | USP30 (0.35) | USP30BACE1BACE2TSHRMAPK1 | |
| SCHEMBL29270712 | 0.84 | GRM2 (0.33) | PDK2BACE1BACE2GRM2TSHR | |
| SCHEMBL29270657 | 0.84 | PDK2 (0.32) | PDK2BACE1BACE2GRM2 | |
| SCHEMBL29270639 | 0.82 | KDM4E (0.38) | BACE1BACE2GRM2 | |
| SCHEMBL29270650 | 0.81 | ALOX5 (0.32) | PDK2BACE1BACE2GRM2 | |
| SCHEMBL29270660 | 0.81 | BACE1 (0.33) | BACE1BACE2GRM2 | |
| SCHEMBL29270473 | 0.81 | KMT2A (0.42) | BACE1BACE2GRM2TSHR | |
| SCHEMBL29270632 | 0.81 | NPC1 (0.44) | BACE1BACE2GRM2TSHR | |
| SCHEMBL29270587 | 0.80 | HPGD (0.40) | BACE1BACE2GRM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964048-A | Bicyclic tetrahydroazepine derivatives for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2023-10-27 | — | — | CN | claimed |