Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29270550 | 0.93 | TP53 (0.32) | TP53 | |
| SCHEMBL29270660 | 0.88 | BACE1 (0.33) | — | |
| SCHEMBL26961903 | 0.87 | TP53 (0.33) | TP53 | |
| SCHEMBL29270676 | 0.85 | TP53 (0.31) | TP53 | |
| SCHEMBL29270526 | 0.85 | TP53 (0.33) | TP53 | |
| SCHEMBL29270637 | 0.84 | TP53 (0.34) | TP53 | |
| SCHEMBL29270620 | 0.83 | TP53 (0.31) | TP53 | |
| SCHEMBL29270453 | 0.82 | S1PR4 (0.33) | TP53 | |
| SCHEMBL29270606 | 0.81 | CNR2 (0.35) | — | |
| SCHEMBL29270544 | 0.81 | ALOX15B (0.32) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964048-A | Bicyclic tetrahydroazepine derivatives for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-116964048-A | Bicyclic tetrahydroazepine derivatives for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2023-10-27 | — | — | CN | disclosed |