Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29270772 | 0.92 | TP53 (0.35) | TP53MAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL29270847 | 0.89 | TP53 (0.47) | TP53MAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL29270781 | 0.85 | TP53 (0.37) | TP53MAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL29270816 | 0.85 | MAPT (0.33) | TP53MAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL29270810 | 0.82 | TP53 (0.35) | TP53MAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL29270690 | 0.82 | ALDH1A1 (0.41) | TP53MAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL29270744 | 0.81 | TP53 (0.34) | TP53MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL29270701 | 0.80 | CNR2 (0.32) | — | |
| SCHEMBL29270828 | 0.80 | TP53 (0.34) | TP53MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL26961771 | 0.79 | MAPT (0.41) | TP53MAPTSMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964048-A | Bicyclic tetrahydroazepine derivatives for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2023-10-27 | — | — | CN | disclosed |