Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 5/20 | 0.32 |
| ▸ | XIAP | P98170 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31143282 | 0.88 | POLB (0.34) | P2RX3XIAPSRCPOLBMAPT | |
| SCHEMBL26961647 | 0.86 | POLB (0.35) | P2RX3XIAPSRCPOLBMAPT | |
| SCHEMBL29796949 | 0.86 | POLB (0.35) | P2RX3XIAPSRCPOLBMAPT | |
| SCHEMBL26962041 | 0.85 | POLB (0.35) | P2RX3XIAPSRCPOLBMAPT | |
| SCHEMBL26961878 | 0.85 | POLB (0.35) | P2RX3XIAPSRCPOLBMAPT | |
| SCHEMBL29796826 | 0.85 | POLB (0.35) | P2RX3XIAPSRCPOLBMAPT | |
| SCHEMBL29796836 | 0.84 | POLB (0.35) | P2RX3XIAPSRCPOLBMAPT | |
| SCHEMBL26961996 | 0.84 | POLB (0.35) | P2RX3XIAPSRCPOLBMAPT | |
| SCHEMBL26962245 | 0.84 | LMNA (0.35) | P2RX3XIAPSRCPOLBMAPT | |
| SCHEMBL29796952 | 0.84 | SRC (0.34) | P2RX3XIAPSRCPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964048-A | Bicyclic tetrahydroazepine derivatives for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2023-10-27 | — | — | CN | disclosed |