Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | WDR5 | P61964 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ENGASE | Q8NFI3 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.32 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29271010 | 0.90 | MAPT (0.35) | MAPTWDR5KMT2AENGASENPC1 | |
| SCHEMBL29271005 | 0.89 | KLKB1 (0.38) | MAPTWDR5KMT2AENGASENPC1 | |
| SCHEMBL29271016 | 0.89 | KDM1A (0.35) | MAPTWDR5KMT2AENGASENPC1 | |
| SCHEMBL29271012 | 0.89 | KLKB1 (0.32) | KLKB1 | |
| SCHEMBL29271039 | 0.87 | MAPT (0.34) | MAPTWDR5KMT2AENGASENPC1 | |
| SCHEMBL29271040 | 0.84 | KLKB1 (0.34) | MAPTCYP3A4CYP2C9KDM4EDDAH1 | |
| SCHEMBL29271025 | 0.82 | MAPT (0.35) | MAPTWDR5KMT2AENGASENPC1 | |
| SCHEMBL29271009 | 0.82 | KLKB1 (0.36) | KLKB1 | |
| SCHEMBL29271017 | 0.80 | KLKB1 (0.31) | KLKB1 | |
| SCHEMBL29271038 | 0.79 | FTO (0.39) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271287-A | Cyclohexanedione derivative, preparation method, application and herbicide thereof | 南京农业大学 | 2024-07-02 | — | — | CN | claimed |
| CN-118271287-A | Cyclohexanedione derivative, preparation method, application and herbicide thereof | 南京农业大学 | 2024-07-02 | — | — | CN | disclosed |