Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14167640 | 0.82 | ACHE (0.40) | — | |
| SCHEMBL29138047 | 0.79 | ACHE (0.33) | — | |
| SCHEMBL25275730 | 0.78 | KDM5B (0.39) | KDM5BALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL34468717 | 0.77 | KDM5B (0.38) | KDM5BALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL25232797 | 0.76 | KDM5B (0.39) | KDM5BALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL15465245 | 0.75 | KDM5B (0.36) | KDM5BALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL16290188 | 0.75 | KDM5B (0.36) | KDM5BALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL15465247 | 0.75 | KDM5B (0.36) | KDM5BALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL34468712 | 0.75 | KDM5B (0.36) | KDM5BALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL17675635 | 0.74 | KDM5B (0.38) | KDM5BALDH1A1LMNAPOLBCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118284604-A | Fused heterocycles as RIPK1 inhibitors | 比西切姆有限公司 | 2024-07-02 | — | — | CN | disclosed |