Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.59 |
| ▸ | LCK | P06239 | 7/20 | 0.59 |
| ▸ | JAK3 | P52333 | 7/20 | 0.59 |
| ▸ | TEK | Q02763 | 4/20 | 0.56 |
| ▸ | RAF1 | P04049 | 9/20 | 0.53 |
| ▸ | BRAF | P15056 | 8/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.46 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30236705 | 1.00 | KDR (0.59) | KDRMAPK14LCKJAK3TEK | |
| SCHEMBL29272482 | 0.89 | RAF1 (0.53) | KDRMAPK14LCKJAK3TEK | |
| SCHEMBL30236184 | 0.89 | RAF1 (0.53) | KDRMAPK14LCKJAK3TEK | |
| SCHEMBL30236274 | 0.86 | LCK (0.48) | KDRMAPK14LCKJAK3TEK | |
| SCHEMBL29272158 | 0.86 | LCK (0.48) | KDRMAPK14LCKJAK3TEK | |
| SCHEMBL30236871 | 0.86 | LCK (0.48) | KDRMAPK14LCKJAK3TEK | |
| SCHEMBL30237067 | 0.86 | LCK (0.48) | KDRMAPK14LCKJAK3TEK | |
| SCHEMBL29272271 | 0.86 | RAF1 (0.57) | KDRMAPK14LCKJAK3TEK | |
| SCHEMBL30236582 | 0.84 | RAF1 (0.57) | KDRMAPK14LCKJAK3TEK | |
| SCHEMBL30236502 | 0.84 | BRAF (0.60) | KDRMAPK14LCKJAK3TEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159537-A | 6-Aza-quinoline derivatives and related uses | 黑钻治疗公司 | 2024-06-07 | — | — | CN | disclosed |