Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 19/20 | 0.47 |
| ▸ | BRAF | P15056 | 16/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | ARAF | P10398 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30236400 | 1.00 | RAF1 (0.47) | RAF1BRAFLCKKDRJAK3 | |
| SCHEMBL30236184 | 0.94 | RAF1 (0.53) | RAF1BRAFLCKKDRJAK3 | |
| SCHEMBL29272482 | 0.94 | RAF1 (0.53) | RAF1BRAFLCKKDRJAK3 | |
| SCHEMBL29272311 | 0.92 | RAF1 (0.44) | RAF1BRAFLCKKDRJAK3 | |
| SCHEMBL30236405 | 0.92 | RAF1 (0.44) | RAF1BRAFLCKKDRJAK3 | |
| SCHEMBL30237000 | 0.89 | BRAF (0.48) | RAF1BRAF | |
| SCHEMBL29272360 | 0.89 | BRAF (0.48) | RAF1BRAF | |
| SCHEMBL30236886 | 0.86 | RAF1 (0.58) | RAF1BRAF | |
| SCHEMBL29272307 | 0.86 | RAF1 (0.58) | RAF1BRAF | |
| SCHEMBL29272078 | 0.85 | RAF1 (0.55) | RAF1BRAFLCKKDRJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159537-A | 6-Aza-quinoline derivatives and related uses | 黑钻治疗公司 | 2024-06-07 | — | — | CN | disclosed |