Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 18/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | RAF1 | P04049 | 16/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29272360 | 1.00 | BRAF (0.48) | BRAFCYP2C9RAF1 | |
| SCHEMBL29272311 | 0.90 | RAF1 (0.44) | BRAFRAF1 | |
| SCHEMBL30236405 | 0.90 | RAF1 (0.44) | BRAFRAF1 | |
| SCHEMBL30236302 | 0.89 | BRAF (0.62) | BRAFCYP2C9RAF1 | |
| SCHEMBL29272329 | 0.89 | BRAF (0.62) | BRAFCYP2C9RAF1 | |
| SCHEMBL29272469 | 0.89 | RAF1 (0.47) | BRAFRAF1 | |
| SCHEMBL30236400 | 0.89 | RAF1 (0.47) | BRAFRAF1 | |
| SCHEMBL29272482 | 0.88 | RAF1 (0.53) | BRAFRAF1 | |
| SCHEMBL30236184 | 0.88 | RAF1 (0.53) | BRAFRAF1 | |
| SCHEMBL30236732 | 0.86 | RAF1 (0.60) | BRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399210-A1 | 6-AZA-QUINOLINE DERIVATIVES AND RELATED USES | Black Diamond Therapeutics, Inc. (US) | 2024-07-17 | — | — | EP | disclosed |
| CN-118159537-A | 6-Aza-quinoline derivatives and related uses | 黑钻治疗公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2023039505-A1 | 6-AZA-QUINOLINE DERIVATIVES AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2023-03-16 | — | — | WO | disclosed |