SCHEMBL29272829

SCHEMBL29272829

Cc1c(C)c2c(c(C)c1O)OCc1cc(O)ccc1-2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.49
ESR2 Q92731 8/20 0.49
HSP90AA1 P07900 2/20 0.35
ALDH1A1 P00352 3/20 0.33
MAPT P10636 2/20 0.33
RAB9A P51151 2/20 0.33
SENP1 Q9P0U3 1/20 0.33
MEN1 O00255 2/20 0.33
GLA P06280 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 2/20 0.33
GAA P10253 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
NR1I2 O75469 1/20 0.33
GMNN O75496 1/20 0.33
USP2 O75604 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3200412 0.74 ESR1 (0.50) ESR1ESR2HSP90AA1ALDH1A1MAPT
SCHEMBL26908656 0.71 ESR2 (0.54) ESR1ESR2ALDH1A1MAPTRAB9A
SCHEMBL31545456 0.69 MAPT (0.44) ESR1ESR2ALDH1A1MAPTRAB9A
SCHEMBL4450682 0.69 ESR2 (0.45) ESR1ESR2HSP90AA1ALDH1A1MAPT
SCHEMBL19946023 0.69 AAK1 (0.51) ESR1ESR2HSP90AA1ALDH1A1MAPT
SCHEMBL23409879 0.68 KDM4E (0.51) ESR1ESR2HSP90AA1ALDH1A1MAPT
SCHEMBL29757625 0.68 KDM4E (0.51) ESR1ESR2HSP90AA1ALDH1A1MAPT
SCHEMBL802750 0.66 MAOA (0.49) ESR1ESR2ALDH1A1MAPTRAB9A
SCHEMBL4170867 0.66 MAPT (0.61) ALDH1A1MAPTRAB9ALMNAGAA
SCHEMBL30577530 0.66 MAOA (0.49) ESR1ESR2ALDH1A1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117015530-A Urolithin derivatives and methods of use thereof 范徳利亚股份公司 2023-11-07 CN disclosed