Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30934763 | 1.00 | MET (0.40) | METHTTKMT2AFGFR1FGFR2 | |
| SCHEMBL30934884 | 0.79 | KDM4C (0.34) | HTTKMT2AKDM4CKDM5BCREBBP | |
| SCHEMBL23012480 | 0.77 | KDM4C (0.40) | METFGFR1FGFR2FGFR3KDM4C | |
| SCHEMBL29273569 | 0.76 | PDGFRB (0.35) | METFGFR1FGFR2FGFR3KDM4C | |
| SCHEMBL30935008 | 0.72 | FGFR1 (0.42) | METFGFR1FGFR2FGFR3JAK2 | |
| SCHEMBL29273539 | 0.72 | FGFR1 (0.42) | METFGFR1FGFR2FGFR3JAK2 | |
| SCHEMBL23012512 | 0.71 | KDM4C (0.43) | METFGFR1FGFR2FGFR3KDM4C | |
| SCHEMBL1328984 | 0.70 | GCK (0.47) | METHTTKMT2A | |
| SCHEMBL15881240 | 0.70 | MET (0.53) | METHTTKMT2AJAK2CREBBP | |
| SCHEMBL3598739 | 0.69 | BRD4 (0.36) | METHTTKMT2AFGFR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344342-A | Substituted polyaromatic ring derivatives, compositions and uses thereof | 康迈迪森(北京)医药科技有限公司 | 2024-07-16 | — | — | CN | disclosed |