Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.38 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.37 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | MAP4K3 | Q8IVH8 | 4/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | AXL | P30530 | 2/20 | 0.33 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.33 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.32 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24270161 | 0.81 | MET (0.39) | METFGFR1FGFR2FGFR3BMPR1A | |
| SCHEMBL30935008 | 0.79 | FGFR1 (0.42) | METFGFR1FGFR2FGFR3BMPR1A | |
| SCHEMBL29273539 | 0.79 | FGFR1 (0.42) | METFGFR1FGFR2FGFR3BMPR1A | |
| SCHEMBL29273569 | 0.77 | PDGFRB (0.35) | METFGFR1FGFR2FGFR3 | |
| SCHEMBL657486 | 0.76 | FFAR1 (0.44) | METBMPR1AACVRL1ACVR1NTRK1 | |
| SCHEMBL31276752 | 0.71 | DYRK1A (0.44) | METNTRK1 | |
| SCHEMBL29547825 | 0.70 | FGFR3 (0.41) | METFGFR1FGFR2FGFR3BMPR1A | |
| SCHEMBL23022232 | 0.70 | MET (0.41) | METFGFR1FGFR2FGFR3BMPR1A | |
| SCHEMBL21426239 | 0.70 | FFAR1 (0.42) | IRAK4 | |
| SCHEMBL21588639 | 0.69 | FFAR1 (0.40) | NTRK1IKBKETBK1PIK3CDIRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344342-A | Substituted polyaromatic ring derivatives, compositions and uses thereof | 康迈迪森(北京)医药科技有限公司 | 2024-07-16 | — | — | CN | disclosed |