Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29274171 | 0.85 | BACE1 (0.33) | BACE1 | |
| SCHEMBL21723152 | 0.77 | ALOX5AP (0.32) | BACE1 | |
| SCHEMBL29137930 | 0.75 | BACE1 (0.31) | BACE1 | |
| SCHEMBL21722860 | 0.75 | BACE1 (0.35) | BACE1 | |
| SCHEMBL29274167 | 0.72 | BACE1 (0.31) | BACE1 | |
| SCHEMBL20972155 | 0.72 | BACE1 (0.30) | BACE1 | |
| SCHEMBL22777345 | 0.71 | NPC1 (0.39) | BACE1 | |
| SCHEMBL30274950 | 0.71 | NPC1 (0.39) | BACE1 | |
| SCHEMBL22777342 | 0.70 | BACE1 (0.36) | BACE1 | |
| SCHEMBL22689384 | 0.69 | MEN1 (0.36) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585136-B | Urea compounds and compositions as SMARCA2/BRM atpase inhibitors | 诺华股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-112585136-A | Urea compounds and compositions as SMARCA2/BRM ATPase inhibitors | 诺华股份有限公司 | 2021-03-30 | — | — | CN | disclosed |