SCHEMBL29274341

SCHEMBL29274341

N#CC(S)CCc1ccc(Br)cc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.42
HTR2A P28223 1/20 0.42
MAOB P27338 3/20 0.35
ALDH1A1 P00352 2/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
GFER P55789 1/20 0.35
HSP90AA1 P07900 1/20 0.33
KMT2A Q03164 1/20 0.33
MAOA P21397 1/20 0.33
IDO1 P14902 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21177054 0.80 MME (0.40) TAAR1HTR2AMAOBALDH1A1KMT2A
SCHEMBL11858643 0.80 SLC6A4 (0.41) TAAR1HTR2AMAOBALDH1A1HPGD
SCHEMBL8418976 0.77 TAAR1 (0.42) TAAR1HTR2AMAOBALDH1A1HSP90AA1
SCHEMBL17713409 0.77 TAAR1 (0.47) TAAR1HTR2AMAOBHSP90AA1KMT2A
SCHEMBL10833193 0.76 ESR2 (0.44) TAAR1HTR2AMAOBALDH1A1GAA
SCHEMBL25278064 0.74 TAAR1 (0.46) TAAR1HTR2AHSP90AA1KMT2AIDO1
SCHEMBL11782475 0.72 HTR2A (0.41) TAAR1HTR2AALDH1A1HSP90AA1KMT2A
SCHEMBL19510650 0.69 TAAR1 (0.46) TAAR1HTR2AMAOBALDH1A1KMT2A
SCHEMBL10833538 0.69 CCR1 (0.40) TAAR1HTR2AALDH1A1KMT2ACYP1A2
SCHEMBL7277805 0.69 TAAR1 (0.50) TAAR1HTR2AHSP90AA1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114409680-B PPAR agonists and uses thereof 上海怡立舍生物技术有限公司 2023-11-21 CN disclosed