Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417219 | 0.81 | TAAR1 (0.42) | TAAR1MMP12MMP13MAOB | |
| SCHEMBL3997283 | 0.80 | CTSC (0.44) | MMP12MMP13CYP2D6 | |
| SCHEMBL2163440 | 0.80 | CTSC (0.44) | MMP12MMP13CYP2D6 | |
| SCHEMBL4323888 | 0.80 | CTSC (0.44) | MMP12MMP13CYP2D6 | |
| SCHEMBL7277805 | 0.77 | TAAR1 (0.50) | TAAR1HTR2AMMP12MMP13HSP90AA1 | |
| SCHEMBL29274341 | 0.77 | TAAR1 (0.42) | TAAR1HTR2AHSP90AA1KMT2AMAOB | |
| SCHEMBL17713409 | 0.77 | TAAR1 (0.47) | TAAR1HTR2AHSP90AA1KMT2AMAOB | |
| SCHEMBL10833193 | 0.76 | ESR2 (0.44) | TAAR1HTR2AKMT2AMAOBALDH1A1 | |
| SCHEMBL18240102 | 0.74 | MMP12 (0.54) | MMP12MMP13 | |
| SCHEMBL25278064 | 0.74 | TAAR1 (0.46) | TAAR1HTR2AHSP90AA1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610049-B1 | Process for producing optically active alpha-hydroxycarboxylic acid having phenyl group | MITSUBISHI RAYON CO (JP) | 1999-11-03 | — | — | EP | claimed |
| EP-0610048-B1 | Process for producing optically active alpha-hydrocarboxylic acid having phenyl group | MITSUBISHI RAYON CO (JP) | 1999-09-22 | — | — | EP | claimed |
| US-5714357-A | Process for producing optically active α-hydroxycarboxylic acid having phenyl group | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-02-03 | — | — | US | claimed |
| US-5580765-A | A CULTURE PRODUCT OF A-HYDROXYNITRILE OR A MIXTURE OF ALDEHYDE AND PRUSSIC ACID | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-12-03 | — | — | US | claimed |
| EP-0610048-A2 | Process for producing optically active alpha-hydrocarboxylic acid having phenyl group | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-08-10 | — | — | EP | claimed |
| EP-0610049-A2 | Process for producing optically active alpha-hydroxycarboxylic acid having phenyl group | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-08-10 | — | — | EP | claimed |
| EP-0610049-B1 | Process for producing optically active alpha-hydroxycarboxylic acid having phenyl group | MITSUBISHI RAYON CO (JP) | 1999-11-03 | — | — | EP | disclosed |
| EP-0610048-B1 | Process for producing optically active alpha-hydrocarboxylic acid having phenyl group | MITSUBISHI RAYON CO (JP) | 1999-09-22 | — | — | EP | disclosed |
| US-5714357-A | Process for producing optically active α-hydroxycarboxylic acid having phenyl group | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-02-03 | — | — | US | disclosed |
| US-5580765-A | A CULTURE PRODUCT OF A-HYDROXYNITRILE OR A MIXTURE OF ALDEHYDE AND PRUSSIC ACID | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0610048-A2 | Process for producing optically active alpha-hydrocarboxylic acid having phenyl group | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-08-10 | — | — | EP | disclosed |
| EP-0610049-A2 | Process for producing optically active alpha-hydroxycarboxylic acid having phenyl group | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-08-10 | — | — | EP | disclosed |