SCHEMBL29275331

SCHEMBL29275331

O=C(/C=C/c1ccc(S(=O)(=O)Oc2ccc(I)cc2)cc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 1/20 0.57
BCHE P06276 3/20 0.56
CYP3A4 P08684 3/20 0.56
NFKB1 P19838 2/20 0.56
NFKB2 Q00653 2/20 0.56
RELA Q04206 2/20 0.56
MAPT P10636 5/20 0.52
KMT2A Q03164 3/20 0.52
RAB9A P51151 3/20 0.52
NPC1 O15118 2/20 0.52
MAOB P27338 4/20 0.51
LMNA P02545 3/20 0.51
TNFRSF1A P19438 2/20 0.51
CYP1B1 Q16678 2/20 0.51
PLIN1 O60240 1/20 0.51
ACHE P22303 1/20 0.51
RECQL P46063 1/20 0.51
PLIN5 Q00G26 1/20 0.51
ABHD5 Q8WTS1 1/20 0.51
HSPD1 P10809 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27840727 0.91 STS (0.64) STSBCHECYP3A4NFKB1NFKB2
SCHEMBL3890673 0.88 MAPT (0.68) STSBCHECYP3A4NFKB1NFKB2
SCHEMBL29275355 0.88 BCHE (0.75) STSBCHECYP3A4NFKB1NFKB2
SCHEMBL27775812 0.88 MAOB (0.58) STSBCHECYP3A4NFKB1NFKB2
SCHEMBL27755220 0.88 MAPT (0.68) STSBCHECYP3A4NFKB1NFKB2
SCHEMBL27840728 0.88 MAOB (0.58) STSBCHECYP3A4NFKB1NFKB2
SCHEMBL27840782 0.84 MAOB (0.72) STSBCHECYP3A4NFKB1NFKB2
SCHEMBL25202161 0.84 KMT2A (0.62) STSBCHECYP3A4NFKB1NFKB2
SCHEMBL13434635 0.84 KMT2A (0.62) STSBCHECYP3A4NFKB1NFKB2
SCHEMBL20805407 0.82 CYP1B1 (0.75) BCHECYP3A4NFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115197108-B Preparation method of gamma-ketosulfone compound 南华大学 2023-11-28 CN disclosed