Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28938109 | 1.00 | EGLN1 (0.44) | EGLN1NPC1ALDH1A1RAB9AKLKB1 | |
| SCHEMBL29275442 | 0.86 | EGLN1 (0.44) | EGLN1RET | |
| SCHEMBL28938095 | 0.86 | EGLN1 (0.46) | EGLN1 | |
| SCHEMBL28938094 | 0.86 | EGLN1 (0.46) | EGLN1 | |
| SCHEMBL29275444 | 0.86 | EGLN1 (0.44) | EGLN1RET | |
| SCHEMBL28938107 | 0.80 | LMNA (0.51) | ALDH1A1RET | |
| SCHEMBL23957691 | 0.78 | EGLN1 (0.43) | EGLN1NPC1ALDH1A1RAB9ARET | |
| SCHEMBL23930000 | 0.77 | EGLN1 (0.44) | EGLN1RETPDE2A | |
| SCHEMBL23930002 | 0.75 | EGLN1 (0.47) | EGLN1NPC1ALDH1A1RAB9APDE2A | |
| SCHEMBL23929998 | 0.75 | EGLN1 (0.47) | EGLN1NPC1ALDH1A1RAB9APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605477-B | Pyrazolo [1,5-a ] pyridine derivative, preparation method, composition and application thereof | 深圳众格生物科技有限公司 | 2024-07-05 | — | — | CN | disclosed |