Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5556096 | 0.72 | GRM2 (0.50) | KDM4EALDH1A1MAOA | |
| SCHEMBL27811117 | 0.71 | CA12 (0.65) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL783152 | 0.69 | TYR (0.41) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL1606849 | 0.69 | CNR2 (0.42) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL27848702 | 0.68 | MEN1 (0.42) | KDM4EALDH1A1HPGDDHODHMAOA | |
| SCHEMBL11444894 | 0.67 | CNR2 (0.73) | CNR2 | |
| SCHEMBL7347589 | 0.66 | CNR2 (0.69) | KDM4EALDH1A1CNR2HSD17B10 | |
| SCHEMBL27811234 | 0.66 | MAPT (0.44) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL15625751 | 0.66 | CA12 (0.53) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL15625725 | 0.65 | CNR2 (0.52) | CA12CA1CA2CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |