Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 11/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15625725 | 0.90 | CNR2 (0.52) | CA12CA1CA2CA9CNR2 | |
| SCHEMBL17179429 | 0.79 | NPC1 (0.54) | KDM4EALDH1A1HSD17B10GSK3BACHE | |
| SCHEMBL30216747 | 0.77 | CNR2 (0.64) | CA12CA1CA2CA9CNR2 | |
| SCHEMBL28215935 | 0.74 | DYRK1A (0.52) | CA12CA1CA2CA9CNR2 | |
| SCHEMBL23929208 | 0.73 | CNR2 (0.53) | CNR2CNR1 | |
| SCHEMBL12206640 | 0.70 | CNR2 (0.54) | CNR2KDM4EALDH1A1HSD17B10CNR1 | |
| SCHEMBL19532488 | 0.69 | MKNK2 (0.54) | CA12CA1CA2CA9CNR2 | |
| SCHEMBL27811117 | 0.69 | CA12 (0.65) | CA12CA1CA2CA9CNR2 | |
| SCHEMBL28118981 | 0.69 | CA12 (0.47) | CA12CA1CA2CA9CNR2 | |
| SCHEMBL23269921 | 0.68 | CDC25A (0.65) | CNR2KDM4EALDH1A1HSD17B10CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140088144-A1 | INHIBITING MICROBIAL INFECTIONS | THE UNIVERSITY OF KANSAS (US) | 2014-03-27 | — | — | US | disclosed |
| US-20140088144-A1 | INHIBITING MICROBIAL INFECTIONS | THE UNIVERSITY OF KANSAS (US) | 2014-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088144-A1 | INHIBITING MICROBIAL INFECTIONS | ARAF, VGF, LITAF | CA12 3987/4885CA1 3778/4885CA2 2297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.