Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 8/20 | 0.81 |
| ▸ | IL1B | P01584 | 8/20 | 0.52 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CCNK | O75909 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29275831 | 1.00 | NLRP3 (0.81) | NLRP3IL1BKAT2BCCNT1CCNK | |
| SCHEMBL30214821 | 1.00 | NLRP3 (0.81) | NLRP3IL1BKAT2BCCNT1CCNK | |
| SCHEMBL29275784 | 0.90 | NLRP3 (0.66) | NLRP3IL1B | |
| SCHEMBL30214155 | 0.90 | NLRP3 (0.66) | NLRP3IL1B | |
| SCHEMBL28963198 | 0.89 | NLRP3 (1.00) | NLRP3IL1BKAT2BCHEK2 | |
| SCHEMBL28963200 | 0.89 | NLRP3 (1.00) | NLRP3IL1BKAT2BCHEK2 | |
| SCHEMBL30108655 | 0.89 | NLRP3 (1.00) | NLRP3IL1BKAT2BCHEK2 | |
| SCHEMBL30108628 | 0.89 | NLRP3 (1.00) | NLRP3IL1BKAT2BCHEK2 | |
| SCHEMBL30108740 | 0.88 | NLRP3 (0.79) | NLRP3IL1BKAT2BCHEK2CHEK1 | |
| SCHEMBL28934418 | 0.88 | NLRP3 (0.79) | NLRP3IL1BKAT2BCHEK2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302417-A | NLRP3 inhibitors | PTC医疗公司 | 2024-07-05 | — | — | CN | disclosed |