Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.38 |
| ▸ | JAK1 | P23458 | 3/20 | 0.37 |
| ▸ | GLS | O94925 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30994924 | 1.00 | MEN1 (0.40) | MEN1KMT2AALDH1A1MAPTTRPV1 | |
| SCHEMBL29276178 | 0.85 | GSK3B (0.38) | JAK1JAK2 | |
| SCHEMBL24840030 | 0.82 | PRMT5 (0.46) | MEN1KMT2ATRPV1PRMT5USP30 | |
| SCHEMBL30168043 | 0.82 | PRMT5 (0.46) | MEN1KMT2ATRPV1PRMT5USP30 | |
| SCHEMBL27292332 | 0.79 | PRMT5 (0.41) | MEN1KMT2ATRPV1PRMT5USP30 | |
| SCHEMBL27292280 | 0.79 | PRMT5 (0.41) | MEN1KMT2ATRPV1PRMT5USP30 | |
| SCHEMBL30718297 | 0.79 | PRMT5 (0.41) | MEN1KMT2ATRPV1PRMT5USP30 | |
| SCHEMBL28934494 | 0.78 | PIM1 (0.43) | MEN1KMT2AALDH1A1MAPTTRPV1 | |
| SCHEMBL24574884 | 0.78 | PIM1 (0.43) | MEN1KMT2AALDH1A1MAPTTRPV1 | |
| SCHEMBL28934282 | 0.78 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPTTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302417-A | NLRP3 inhibitors | PTC医疗公司 | 2024-07-05 | — | — | CN | disclosed |