Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 4/20 | 0.37 |
| ▸ | JAK1 | P23458 | 3/20 | 0.37 |
| ▸ | BTK | Q06187 | 14/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30994924 | 0.85 | MEN1 (0.40) | JAK1JAK2 | |
| SCHEMBL29276231 | 0.85 | MEN1 (0.40) | JAK1JAK2 | |
| SCHEMBL16346163 | 0.84 | L3MBTL3 (0.31) | BTK | |
| SCHEMBL29276119 | 0.82 | SIGMAR1 (0.39) | GSK3B | |
| SCHEMBL30214759 | 0.82 | SIGMAR1 (0.39) | GSK3B | |
| SCHEMBL29189096 | 0.80 | JAK1 (0.42) | GSK3BJAK3JAK1BTKJAK2 | |
| SCHEMBL29189098 | 0.80 | JAK1 (0.42) | GSK3BJAK3JAK1BTKJAK2 | |
| SCHEMBL28934527 | 0.74 | JAK3 (0.39) | JAK3JAK1BTKEGFR | |
| SCHEMBL28934525 | 0.74 | JAK3 (0.39) | JAK3JAK1BTKEGFR | |
| SCHEMBL26647696 | 0.71 | JAK2 (0.45) | GSK3BJAK3JAK1BTKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302417-A | NLRP3 inhibitors | PTC医疗公司 | 2024-07-05 | — | — | CN | disclosed |