Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30637674 | 1.00 | GSK3B (0.52) | GSK3BMAPK14NR3C2ALDH1A1KMT2A | |
| SCHEMBL29276322 | 0.92 | GSK3B (0.48) | GSK3BMAPK14ALDH1A1KMT2AHPGD | |
| SCHEMBL30637594 | 0.91 | RIOK2 (0.48) | GSK3BALDH1A1PKMRIOK2SMN1; SMN2 | |
| SCHEMBL29276337 | 0.91 | RIOK2 (0.48) | GSK3BALDH1A1PKMRIOK2SMN1; SMN2 | |
| SCHEMBL29276306 | 0.91 | GSK3B (0.56) | GSK3BMAPK14NR3C2ALDH1A1KMT2A | |
| SCHEMBL30637664 | 0.89 | GSK3B (0.47) | GSK3BMAPK14NR3C2ALDH1A1KMT2A | |
| SCHEMBL29276314 | 0.89 | GSK3B (0.47) | GSK3BMAPK14NR3C2ALDH1A1KMT2A | |
| SCHEMBL29276334 | 0.89 | ALDH1A1 (0.55) | GSK3BMAPK14NR3C2ALDH1A1KMT2A | |
| SCHEMBL29276341 | 0.87 | GSK3B (0.45) | GSK3BMAPK14NR3C2ALDH1A1KMT2A | |
| SCHEMBL29276354 | 0.86 | KMT2A (0.52) | GSK3BMAPK14NR3C2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143097-A | Beta-carbopol compound, preparation method thereof and application of beta-carbopol compound in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2023-12-01 | — | — | CN | disclosed |