Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 3/20 | 0.32 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30678842 | 1.00 | LATS1 (0.32) | LATS1LATS2MAPK1KDM4EMEN1 | |
| SCHEMBL21718437 | 0.83 | LATS1 (0.30) | LATS1 | |
| SCHEMBL14734141 | 0.76 | LATS1 (0.33) | LATS1LATS2 | |
| SCHEMBL30639334 | 0.76 | LATS1 (0.33) | LATS1LATS2 | |
| SCHEMBL30678844 | 0.75 | PDE4B (0.34) | LATS1LATS2 | |
| SCHEMBL29277041 | 0.75 | PDE4B (0.34) | LATS1LATS2 | |
| SCHEMBL30678839 | 0.74 | LATS1 (0.31) | LATS1LATS2 | |
| SCHEMBL373964 | 0.70 | — | — | |
| SCHEMBL30678856 | 0.67 | MAPK1 (0.38) | MAPK1KDM4EGAAHSD17B10TSHR | |
| SCHEMBL14734142 | 0.67 | LATS1 (0.32) | LATS1LATS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247394-A | Nitrogen-containing heterocycles as PDE4B inhibitors | 武汉人福创新药物研发中心有限公司 | 2023-12-19 | — | — | CN | disclosed |