Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 5/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.34 |
| ▸ | LATS1 | O95835 | 2/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30678844 | 1.00 | PDE4B (0.34) | PDE4BPDE4DLATS1LATS2 | |
| SCHEMBL14734141 | 0.94 | LATS1 (0.33) | LATS1LATS2 | |
| SCHEMBL30639334 | 0.94 | LATS1 (0.33) | LATS1LATS2 | |
| SCHEMBL373964 | 0.88 | — | — | |
| SCHEMBL31622422 | 0.84 | — | — | |
| SCHEMBL31630700 | 0.79 | — | — | |
| SCHEMBL12209146 | 0.76 | PDE4B (0.32) | PDE4BPDE4D | |
| SCHEMBL11104756 | 0.76 | PDE4B (0.36) | PDE4BPDE4D | |
| SCHEMBL30758561 | 0.75 | LATS1 (0.32) | LATS1LATS2 | |
| SCHEMBL29277038 | 0.75 | LATS1 (0.32) | LATS1LATS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247394-A | Nitrogen-containing heterocycles as PDE4B inhibitors | 武汉人福创新药物研发中心有限公司 | 2023-12-19 | — | — | CN | disclosed |