Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29277368 | 0.80 | PTPN1 (0.56) | PTPN1MAOBMAOAPOLBPTPN2 | |
| SCHEMBL31522272 | 0.80 | MAOB (0.56) | PTPN1MAOBMAOAPOLBPTPN2 | |
| SCHEMBL29277392 | 0.80 | PTPN1 (0.56) | PTPN1MAOBMAOAPOLBPTPN2 | |
| SCHEMBL29952626 | 0.76 | PTPN1 (0.51) | PTPN1MAOBMAOAPOLBPTPN2 | |
| SCHEMBL1573192 | 0.76 | PTPN1 (0.51) | PTPN1MAOBMAOAPOLBPTPN2 | |
| SCHEMBL31234945 | 0.76 | TTR (0.40) | MAOBMAOAMEN1KMT2ATTR | |
| SCHEMBL28588504 | 0.76 | TTR (0.43) | MAOBMAOAMEN1KMT2ATTR | |
| SCHEMBL30307601 | 0.73 | PTPN1 (0.62) | PTPN1MAOBMAOAPOLBPTPN2 | |
| SCHEMBL11876962 | 0.72 | PTPN1 (0.47) | PTPN1MAOBMAOAPOLBPTPN2 | |
| SCHEMBL127924 | 0.72 | PTPN1 (1.00) | PTPN1MAOBMAOAPOLBPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285451-A | Polysubstituted pyrrole compound and synthetic method and application thereof | 重庆文理学院 | 2023-12-26 | — | — | CN | disclosed |