Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.51 |
| ▸ | MAOA | P21397 | 5/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.45 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573192 | 1.00 | PTPN1 (0.51) | PTPN1MAOAMAOBPOLBTLR2 | |
| SCHEMBL914152 | 0.89 | TLR2 (0.49) | PTPN1MAOAMAOBPOLBTLR2 | |
| SCHEMBL11876962 | 0.83 | PTPN1 (0.47) | PTPN1MAOAMAOBPOLBTLR2 | |
| SCHEMBL28467498 | 0.78 | MAOA (0.54) | MAOAESR1KDM5AESR2ALDH1A1 | |
| SCHEMBL31522272 | 0.76 | MAOB (0.56) | PTPN1MAOAMAOBPOLBERN1 | |
| SCHEMBL14341669 | 0.76 | MAOA (0.41) | MAOAMAOBTLR2ERN1TLR1 | |
| SCHEMBL29277381 | 0.76 | PTPN1 (0.56) | PTPN1MAOAMAOBPOLBALDH1A1 | |
| SCHEMBL29277368 | 0.76 | PTPN1 (0.56) | PTPN1MAOAMAOBPOLBALDH1A1 | |
| SCHEMBL29277392 | 0.76 | PTPN1 (0.56) | PTPN1MAOAMAOBPOLBERN1 | |
| SCHEMBL11614605 | 0.76 | PTPN1 (0.56) | PTPN1MAOAMAOBPOLBTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |