Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | LIPC | P11150 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29277453 | 0.80 | GRIN2B (0.46) | SLC6A4PDE4BGPR6 | |
| SCHEMBL21984952 | 0.78 | TACR1 (0.44) | TACR1SLC6A4HTR2CHTR2BPDE2A | |
| SCHEMBL29277440 | 0.78 | TEAD1 (0.46) | LIPGLIPC | |
| SCHEMBL29277460 | 0.78 | PDE4B (0.47) | TACR1PDE4BGPR6 | |
| SCHEMBL29277461 | 0.75 | IDO1 (0.49) | TACR1LIPGLIPC | |
| SCHEMBL22283579 | 0.74 | PDE2A (0.41) | SLC6A4HTR2CHTR2BPDE2AHTR2A | |
| SCHEMBL22283580 | 0.74 | PDE2A (0.41) | SLC6A4HTR2CHTR2BPDE2AHTR2A | |
| SCHEMBL22283606 | 0.74 | SLC6A4 (0.39) | SLC6A4HTR2CHTR2BPDE2AHTR2A | |
| SCHEMBL27149063 | 0.73 | GRIN2B (0.45) | LIPGCHRNA7S1PR1S1PR5LIPC | |
| SCHEMBL31071547 | 0.72 | HTR2C (0.49) | SLC6A4HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |