Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | NAAA | Q02083 | 4/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 4/20 | 0.36 |
| ▸ | LIPC | P11150 | 4/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29277442 | 0.80 | NAAA (0.58) | IDO1NAAALIPGTACR1KMT2A | |
| SCHEMBL29277432 | 0.77 | IDO1 (0.50) | IDO1NAAATACR1 | |
| SCHEMBL31071586 | 0.77 | IDO1 (0.55) | IDO1NAAA | |
| SCHEMBL29277435 | 0.75 | NAAA (0.42) | NAAALIPGTACR1LPLLIPC | |
| SCHEMBL29277447 | 0.75 | NAAA (0.40) | NAAA | |
| SCHEMBL29277458 | 0.75 | TACR1 (0.41) | LIPGTACR1LIPC | |
| SCHEMBL3124123 | 0.75 | IDO1 (0.52) | IDO1NAAA | |
| SCHEMBL29277445 | 0.74 | MGLL (0.41) | NAAALIPGMGLL | |
| SCHEMBL20708874 | 0.74 | NAAA (0.38) | IDO1NAAA | |
| Trifluoroacetic Acid SCHEMBL30945211 | 0.72 | IDO1 (0.47) | IDO1LIPGPOLBKMT2ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |