Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810574 | 0.89 | HIF1A (0.49) | HIF1AEPAS1LIPGMEN1TP53 | |
| SCHEMBL5443240 | 0.85 | HIF1A (0.39) | TYRHIF1AEPAS1LIPGMEN1 | |
| SCHEMBL5725315 | 0.85 | HIF1A (0.39) | TYRHIF1AEPAS1LIPGMEN1 | |
| SCHEMBL28311605 | 0.84 | TYR (0.41) | TYRHIF1AEPAS1LIPGMEN1 | |
| SCHEMBL28690662 | 0.83 | LIPG (0.49) | HIF1AEPAS1LIPGMAPTALOX15 | |
| SCHEMBL28861107 | 0.83 | LIPG (0.49) | HIF1AEPAS1LIPGMAPTALOX15 | |
| SCHEMBL3362755 | 0.82 | TYR (0.38) | TYRHIF1AEPAS1LIPGMEN1 | |
| SCHEMBL7571565 | 0.82 | TYR (0.57) | TYRHIF1ALIPGMEN1TP53 | |
| SCHEMBL11328017 | 0.82 | TYR (0.57) | TYRHIF1ALIPGMEN1TP53 | |
| SCHEMBL10608218 | 0.82 | TYR (0.57) | TYRHIF1ALIPGMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2147909-A1 | METHOD FOR PRODUCTION OF ISOCYANATE USING COMPOSITION COMPRISING CARBAMIC ACID ESTER AND AROMATIC HYDROXY COMPOUND, AND COMPOSITION FOR TRANSPORT OR STORAGE OF CARBAMIC ACID ESTER | Asahi Kasei Chemicals Corporation (JP) | 2010-01-27 | — | — | EP | disclosed |