Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28858626 | 0.81 | TP53 (0.44) | MAPTTP53KMT2ATDP1GAA | |
| SCHEMBL28955162 | 0.81 | TP53 (0.44) | MAPTTP53KMT2ATDP1GAA | |
| SCHEMBL28858616 | 0.81 | TP53 (0.44) | MAPTTP53KMT2ATDP1GAA | |
| SCHEMBL29279205 | 0.79 | ALDH1A1 (0.54) | MAPTTP53KMT2ATDP1GAA | |
| SCHEMBL6467404 | 0.66 | TSHR (0.51) | TP53KMT2ATDP1LMNAALDH1A1 | |
| SCHEMBL20320310 | 0.65 | KMT2A (0.54) | MAPTTP53KMT2ATDP1GAA | |
| SCHEMBL23544514 | 0.65 | ALDH1A1 (0.50) | TP53KMT2ATDP1LMNAALDH1A1 | |
| SCHEMBL6472214 | 0.65 | ALDH1A1 (0.44) | MAPTTP53KMT2ATDP1GAA | |
| SCHEMBL6467391 | 0.65 | TSHR (0.53) | TP53TDP1GAALMNAHTT | |
| SCHEMBL29361005 | 0.65 | ALDH1A1 (0.50) | TP53KMT2ATDP1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586232-A | Edaravone prodrug derivative and application thereof | 天地恒一制药股份有限公司 | 2024-02-23 | — | — | CN | disclosed |